MRD Baseline

Important

MRD products and their corresponding fields are still hidden from the production API. The documentation is already live here to assist partners during the testing phase.

MRD testing is currently only supported for breast cancer tissue, with support for colon and renal planned as fast-follows. Orders for other tissue types will not be auto-rejected but WILL be manually cancelled by Customer Support.

Myriad Precise MRD™ Baseline is the initial test in the Molecular Residual Disease (MRD) testing workflow. It establishes a molecular baseline for a patient's tumor, enabling subsequent monitoring orders to track treatment response over time.

Key Fields

products: [{ product: MRDBASELINE }] — selects the MRD Baseline product
specimens.mrdblood — MRD blood specimen with collection ownership and hospitalization details
- initialCollectionOwner — who manages the initial sample collection of this baseline order (MYRIAD or PROVIDER)
- futureCollectionOwner — who manages future monitoring sample collections (MYRIAD or PROVIDER)
- collectionDate - the date the initial sample is collected
- hospitalizationCode — patient's hospitalization status (HOSPITAL_INPATIENT, HOSPITAL_OUTPATIENT, NON_HOSPITAL_PATIENT)
- hospitalDischargeDate — required when hospitalizationCode is HOSPITAL_INPATIENT
clinical.monitoringSequence — how frequently monitoring should occur. Options include:
- EVERY_4_WEEKS, EVERY_6_WEEKS, EVERY_8_WEEKS
- EVERY_3_MONTHS, EVERY_6_MONTHS, EVERY_12_MONTHS
- SINGLE, RECOMMENDED, NONE
- RECOMMENDED_NEOADJUVANT_MONITORING, RECOMMENDED_ADJUVANT_MRD_AND_MONITORING, RECOMMENDED_SURVEILLANCE
clinical.plannedSurgeryDate — the date surgery is planned for
clinical.treatmentTimepoint — the patient's treatment timepoint at time of order (ADJUVANT, METASTATIC, NEOADJUVANT, SURVEILLANCE, OTHER)

Baseline Order

An example payload showing proper placement of the above fields.

mutation createOrder {
  createOrder(
    order: {
      billing: { institution: { institutionalAccountNumber: "123456789" } }
      clinical: {
        monitoringSequence: EVERY_3_MONTHS
        plannedSurgeryDate: "2025-06-15"
        treatmentTimepoint: NEOADJUVANT
      }
      patient: {
        address: { city: "Salt Lake City", postalCode: "84101", stateCode: UT, street: "320 Wakara Way" }
        dob: "1975-03-22"
        firstName: "Jane"
        genderCode: FEMALE
        lastName: "Smith"
        mobilePhoneNumber: "801-555-1234"
      }
      products: [{ product: MRDBASELINE }]
      providerAccounts: [
        {
          provider: {
            firstName: "Test"
            lastName: "Provider"
            identifiers: [{ type: NPI, use: OFFICIAL, value: "12345" }]
          }
          location: { address: { city: "Salt Lake City", postalCode: "84101", stateCode: UT, street: "320 Wakara Way" } }
          organization: { identifiers: [{ type: XX, use: OFFICIAL, value: "12345" }] }
          role: ORDERING
        }
      ]
      requisitionNumber: "mrd-baseline-001"
      specimens: [
        {
          mrdblood: {
            collectionDate: "2025-05-01"
            initialCollectionOwner: PROVIDER
            futureCollectionOwner: MYRIAD
            hospitalizationCode: NON_HOSPITAL_PATIENT
          }
        }
        {
          tumor: {
            collectionOwner: PROVIDER
            tumorHistory: {
              breastDCIS: {
                diagnosisAge: 56
                diagnosisDate: "1970-01-01"
                diagnosisDetails: {
                  left: true
                  right: false
                  cancerSeverity: [
                    METASTATIC
                  ]
                }
              }
            }
          }
        }
      ]
    }
  ) {
    id
  }
}

Prolaris MRD Monitoring