MRD Monitoring

Important

MRD products and their corresponding fields are still hidden from the production API. The documentation is already live here to assist partners during the testing phase.

MRD testing is currently only supported for breast cancer tissue, with support for colon and renal planned as fast-follows. Orders for other tissue types will not be auto-rejected but WILL be manually cancelled by Customer Support.

Myriad Precise MRD™ Monitoring orders are used to track a patient's treatment response over time after an initial Myriad Precise MRD™ Baseline order has been submitted. Each monitoring order is linked to the original baseline order via relatedOrderRequisitionNumber.

Key Fields

products: [{ product: MRDMONITORING }] — selects the MRD Monitoring product
relatedOrderRequisitionNumber — the requisition number of the previously submitted MRD Baseline order, used internally by Myriad to link the patient's monitoring and baseline together
clinical.treatmentTimepoint — the patient's treatment timepoint at time of order (ADJUVANT, METASTATIC, NEOADJUVANT, SURVEILLANCE, OTHER)
specimens.mrdblood — MRD blood specimen with collection ownership and hospitalization details
- initialCollectionOwner — who manages the initial sample collection (MYRIAD or PROVIDER)
- futureCollectionOwner — who manages future monitoring sample collections (MYRIAD or PROVIDER)
- hospitalizationCode — patient's hospitalization status (HOSPITAL_INPATIENT, HOSPITAL_OUTPATIENT, NON_HOSPITAL_PATIENT)
- hospitalDischargeDate — required when hospitalizationCode is HOSPITAL_INPATIENT

Monitoring Order

An example payload showing proper placement of the above fields.

mutation createOrder {
  createOrder(
    order: {
      billing: { institution: { institutionalAccountNumber: "123456789" } }
      clinical: {
        monitoringSequence: EVERY_3_MONTHS
        treatmentTimepoint: ADJUVANT
        personalCancerHistory: [
          {
            breastDCIS: {
                diagnosisAge: 56
                diagnosisDate: "1970-01-01"
                diagnosisDetails: {
                  left: true
                  right: false
                  cancerSeverity: [
                    METASTATIC
                  ]
                }
                primaryTumorDiagnosis: true
              }
          }
        ]
      }
      patient: {
        address: { city: "Salt Lake City", postalCode: "84101", stateCode: UT, street: "320 Wakara Way" }
        dob: "1975-03-22"
        firstName: "Jane"
        genderCode: FEMALE
        lastName: "Smith"
        mobilePhoneNumber: "801-555-1234"
      }
      products: [{ product: MRDMONITORING }]
      providerAccounts: [
        {
          provider: {
            firstName: "Test"
            lastName: "Provider"
            identifiers: [{ type: NPI, use: OFFICIAL, value: "12345" }]
          }
          location: { address: { city: "Salt Lake City", postalCode: "84101", stateCode: UT, street: "320 Wakara Way" } }
          organization: { identifiers: [{ type: XX, use: OFFICIAL, value: "12345" }] }
          role: ORDERING
        }
      ]
      relatedOrderRequisitionNumber: "mrd-baseline-001"
      requisitionNumber: "mrd-monitoring-001"
      specimens: [
        {
          mrdblood: {
            collectionDate: "2025-08-01"
            initialCollectionOwner: PROVIDER
            futureCollectionOwner: PROVIDER
            hospitalizationCode: HOSPITAL_OUTPATIENT
          }
        }
      ]
    }
  ) {
    id
  }
}

MRD Baseline Attachments